James Gillespie
James Gillespie may refer to:
James Gillespie (North Carolina politician) (c. 1747–1805), American politician from North Carolina
James Gillespie (minister) (1720–1791), Scottish minister and theologian
James Gillespie (footballer) (1868–1932), Scottish footballer
James Gillespie (philanthropist) (1726–1797), Scottish snuff and tobacco merchant
James Gillespie (mariner), HM Excise officer and commander of the cutter Henry Dundas
James J. Gillespie (1892–1959), American politician from Iowa
James U. Gillespie (died 1981), American politician from Florida
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